Platform technology
Developing Therapies With no Compromise
Sagitta© biodegradable conjugation platforms are discovered to reinforce ideal performances in terms of the therapeutic index, pharmacokinetics and manufacturability.
Sagitta©
Developing Therapies With no Compromise
Sagitta© biodegradable conjugation platforms are discovered to reinforce ideal performances in terms of the therapeutic index, pharmacokinetics and manufacturability.
The lead candidate: RS-0139
The lead candidate: RS-0337
The lead candidate: RS-0139

Upon contact with water, Sagitta© Bir backbone wraps around the payload, ensuring formation of a water soluble nanocarrier.
The lead candidate: RS-0337
Upon contact with water, Sagitta© Dui forms a micellar nanoparticle, encapsulating the second payload.
Sagitta© Radix’s design allows for precise targeting of disease sites via monoclonal antibodies (mAbs) or peptides for theranostic applications.
HIGHER
THERAPEUTIC INDEX
The dual drug loading capacity of Sagitta© yields to a synergistic therapeutic effect. Sagitta© platform is compatible with a wide range of targeting ligands or mAbs as well as a diverse choice of drugs – ensuring highest efficacy and specificity.
IMPROVED
PHARMACOKINETICS
Sagitta© platform significantly prolongs the circulation time compared to native API. The improvement in half-life translated across species and therefore poses predictable promise for later clinical stages.
STRAIGHT-FORWARD
MANUFACTURING
We manufacture our products at our own GMP certificated production facility for clinical batch lyophilized oncology drugs.
Efficacy & Specificity
Efficacy & Specificity
· Synergistic therapeutic effect ·
· Higher accumulation ·
Translatability
Translatability
· Predictable translation to human ·
Tolerability
Tolerability
· Enhanced Permeability & Retention effect ·
· Selective release ·
· Biologic stimuli driven release ·
Manufacturability
Manufacturability
· High purity ·
· Scalable for clinical GMP batches ·
HIGHER
THERAPEUTIC INDEX
The dual drug loading capacity of Sagitta© yields to a synergistic therapeutic effect. Sagitta© platform is compatible with a wide range of targeting ligands or mAbs as well as a diverse choice of drugs – ensuring highest efficacy and specificity.
IMPROVED
PHARMACOKINETICS
Sagitta© platform significantly prolongs the circulation time compared to native API. The improvement in half-life translated across species and therefore poses predictable promise for later clinical stages.
STRAIGHT-FORWARD
MANUFACTURING
We manufacture our products at our own GMP certificated production facility for clinical batch lyophilized oncology drugs.
Efficacy & Specificity
Efficacy & Specificity
· Synergistic therapeutic effect
· Higher accumulation
Tolerability
Tolerability
· Enhanced Permeability & Retention effect
· Selective release
· Biologic stimuli driven release
Translatability
Translatability
· Predictable translation to human
Manufacturability
Manufacturability
· High purity
· Scalable for clinical GMP batches
